Pleiotropi
Skitse der viser additiv pleiotropi. G1, G2 og G3 er forskellige gener, der bidrager til fænotyperne P1, P2 og P3
Pleiotropi (fra græsk πλείων pleion, "mere", og τρόπος tropos, "måde") er et begreb inden for genetik, der dækker over at ét gen påvirker to eller flere tilsyneladende uafhængige fænotypiske træk. Derfor kan en mutation i et pleiotropisk gen have effekt på flere egenskaber samtidig. Dette kan vise sig ved sygdomme som Marfan syndrom eller Cystisk fibrose.
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SimpleGenotypePhenotypeMap.jpg
Forfatter/Opretter: Alphillips6, Licens: CC BY-SA 4.0
A very simple genotype-phenotype map that only shows additive pleiotropy effects. G1, G2, and G3 are different genes that contribute to phenotypes P1, P2, and P3. For all intents and purposes, G1 contributes a red color to the phenotype of an organism, G2 contributes a blue color to the phenotype of an organism, and G3 contributes a yellow color to the phenotype of an organism. Please note that these are not real genes, and any similarity to existing genes is purely coincidental. Interpretation of this simple map shows that G1 is the only gene that contributes to the P1 phenotype; thus, this phenotype is red. G1, G2, and G3 contribute to P2; thus, this phenotype is brown. G2 and G3 contribute to P3; thus, this phenotype is green.
Forfatter/Opretter: Alphillips6, Licens: CC BY-SA 4.0
A very simple genotype-phenotype map that only shows additive pleiotropy effects. G1, G2, and G3 are different genes that contribute to phenotypes P1, P2, and P3. For all intents and purposes, G1 contributes a red color to the phenotype of an organism, G2 contributes a blue color to the phenotype of an organism, and G3 contributes a yellow color to the phenotype of an organism. Please note that these are not real genes, and any similarity to existing genes is purely coincidental. Interpretation of this simple map shows that G1 is the only gene that contributes to the P1 phenotype; thus, this phenotype is red. G1, G2, and G3 contribute to P2; thus, this phenotype is brown. G2 and G3 contribute to P3; thus, this phenotype is green.