Tick-Borne Encephalitis Virus

Forfatter/Opretter:

Stiasny K, Kössl C, Lepault J, Rey FA, Heinz FX

Attribution:

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Kredit:

Stiasny K, Kössl C, Lepault J, Rey FA, Heinz FX (2007) Characterization of a Structural Intermediate of Flavivirus Membrane Fusion. PLoS Pathog 3(2): e20. doi:10.1371/journal.ppat.0030020

Shortlink:

https://dkwiki.dk/b/3f63e

kilde:

Wikimedia Commons

størrelse:

3898 x 2043 Pixel (6988333 Bytes)

beskrivelse:

Electron Micrographs of Tick-Borne Encephalitis Virus at pH 8.0, 10.0, and 5.4 TBE virus was preincubated at pH 8.0 (A), 10.0 (B), and 5.4 (C), fixed with formalin, and negatively stained by phosphotungstic acid adjusted to pH 8.0 (samples A and B) or pH 6.0 (sample C). Arrows in (B) point to the rough surface generated by alkaline pH and in (C) to the bulky spikes generated by low pH treatment. All micrographs have been recorded at the same magnification. In (B) and (C), the virions lost their shell-like icosahedral envelope structure, at least at the particle surface, and as a consequence display irregular shapes that give the impression that the virus diameter is smaller than in (A). However, in all cases, the core diameter of the best-preserved virions has a similar value. In (C), the virions are aggregated, a characteristic of TBE virus maintained at low pH.

Licens:

CC BY 2.5

Kommentar på licensen:

This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.

Licensbetingelser:

Creative Commons Attribution 2.5